abstract：PURPOSE:To present a case of unilateral development of severe corneal vascularization in the eye of a keratoconic patient implanted with Intacs microthin prescription inserts and concurrent bilateral use of rigid gas permeable (RGP) contact lenses. METHODS:A 20-year-old male underwent unilateral implantation of Intacs...

journal_title：Seminars in ophthalmology

authors： Kymionis GD,Kontadakis GA

更新日期：2012-01-01 00:00:00

abstract：:Vogt-Koyanagi-Harada syndrome is a bilateral, chronic, diffuse granulomatous panuveitis associated with poliosis, vitiligo, and central nervous system and auditory signs. Increasing reports have been published to describe the clinical features of Vogt-Koyanagi-Harada syndrome. These manifestations are variable. This a...

journal_title：Seminars in ophthalmology

authors： Pan D,Hirose T

更新日期：2011-07-01 00:00:00

abstract：:Recurrent herpes stromal keratitis (HSK) is one of the leading causes of blindness in the developed world. Cyokines characteristic of Th1 cells (in particular IFN-γ and IL-2) have been shown to dominate in HSK in addition to mechanisms by nonspecific, antigen-independent effector cells such as neutrophils, basophils, ...

journal_title：Seminars in ophthalmology

authors： Hawthorne KM,Dana R,Chodosh J

更新日期：2011-07-01 00:00:00

abstract：:Currently, there is no proven drug treatment for dry age-related macular degeneration (AMD). Several different treatment strategies are being investigated, including complement inhibition, neuroprotection, and visual cycle inhibitors, and novel clinical trial endpoints are being explored. Studies have identified genet...

journal_title：Seminars in ophthalmology

authors： Yehoshua Z,Rosenfeld PJ,Albini TA

更新日期：2011-05-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is a progressive degenerative disease which leads to blindness, affecting the quality of life of millions of Americans. More than 1.75 million individuals in the United States are affected by the advanced form of AMD. The etiological pathway of AMD is not yet fully understood, bu...

journal_title：Seminars in ophthalmology

authors： Deangelis MM,Silveira AC,Carr EA,Kim IK

更新日期：2011-05-01 00:00:00

abstract：:We describe a report of a child with a horner's syndrome and sixth nerve paresis secondary to a petrous internal carotid artery (ICA) aneurysm. Management of this condition involved coiling of the aneurysm and the use of botulinum toxin to manage his strabismus and associated symptoms. ...

journal_title：Seminars in ophthalmology

authors： Mangat SS,Nayak H,Chandna A

更新日期：2011-01-01 00:00:00

abstract：:Glaucoma drainage devices are more frequently being used for glaucoma filtering surgeries, even those at low risk for failure with trabeculectomy. There are 4 major devices available: the Molteno, Baerveldt, Krupin, and Ahmed. The Molteno and Baerveldt are non-valved implants, while the Krupin and Ahmed are valved. Th...

journal_title：Seminars in ophthalmology

authors： Patel S,Pasquale LR

更新日期：2010-09-01 00:00:00

abstract：:Idiopathic intracranial hypertension (IIH), or pseudotumor cerebri, describes a condition of elevated intracranial pressure (ICP) that typically presents in obese women of childbearing age with symptoms and signs of posture-dependent headaches, pulsatile tinnitus, visual changes, and papilledema. Optical coherence tom...

journal_title：Seminars in ophthalmology

authors： Heidary G,Rizzo JF 3rd

更新日期：2010-09-01 00:00:00

abstract：:The lacrimal drainage system consists of the lacrimal puncta, inferior and superior canaliculi, common canaliculus, lacrimal sac, and nasolacrimal duct. It is classically divided into upper and lower portions. Obstruction of the drainage system can be congenital or acquired, and may result in persistent epiphora and m...

journal_title：Seminars in ophthalmology

authors： Dantas RR

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy and safety of a modified double extra sharp chopper for removal of hard cataracts. DESIGN:Prospective non-comparative interventional clinical study. PARTICIPANTS:Forty eyes from 25 patients with hard mature cataract grades 3-4. METHODS:The pre-modified Koch chopper was sharpened unde...

journal_title：Seminars in ophthalmology

authors： Simanjuntak GW,Tan JF,Mailangkay HH

更新日期：2010-01-01 00:00:00

abstract：:Paroxysmal hemicrania is a trigeminal autonomic cephalalgia first described in 1976, characterized by episodic attacks of excruciating unilateral periorbital and temporal stabbing, pulsatile, craw-like, or boring headaches lasting 2 - 30 minutes, accompanied by autonomic features, and alleviated by indomethacin. Parox...

journal_title：Seminars in ophthalmology

authors： Dafer RM,Hocker S,Kumar R,McGee J,Jay WM

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:We would like to describe a case report of posterior ischemic optic neuropathy (PION) misdiagnosed as arteritic PION with presumed GCA which leads to missing the correct diagnosis with fatal outcome. METHODS:The clinical course of a single patient will be described including presentation, testing,diagnosis a...

journal_title：Seminars in ophthalmology

authors： Samy H,Chronister D

更新日期：2009-11-01 00:00:00

abstract：:Corneal neovascularization causes deterioration of visual acuity and increases surface irregularities. Various techniques have been employed to help control the progression of corneal neovascularization; bevacizumab is a medication that targets the specific pathway of corneal neovascularization. The Boston Ocular Surf...

journal_title：Seminars in ophthalmology

authors： Lim M,Jacobs DS,Rosenthal P,Carrasquillo KG

更新日期：2009-05-01 00:00:00

abstract：:Retinopathy of prematurity is marked by the proliferative vascularization of the retina in preterm babies. An understanding of the molecular pathogenesis of ROP provides the basis for identifying novel therapeutic targets for treatment. Using the mouse model of oxygen-induced retinopathy, the roles of the hypoxia indu...

journal_title：Seminars in ophthalmology

authors： Heidary G,Vanderveen D,Smith LE

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:To demonstrate the ability of ultra wide-field fundus imaging to document the response to treatment of a choroidal metastatic lesion from primary breast carcinoma. DESIGN:Observational case report. METHODS:A 45 year old female with a history of metastatic breast cancer and progressive vision loss in the right...

journal_title：Seminars in ophthalmology

authors： Coffee RE,Jain A,McCannel TA

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:To describe the use of photoscreening for preschool vision screening in several diverse locations throughout the world. METHODS:The MTI photo screener was used to screen pre-verbal children; photographs were interpreted using standard criteria. RESULTS:The Tennessee vision screening program remains successful...

journal_title：Seminars in ophthalmology

authors： Donahue SP,Lorenz S,Johnson T

更新日期：2008-09-01 00:00:00

abstract：:In the herpetic stromal keratitis (HSK), HSV DNA fragments and HSV-IgG immune complexes (HSV-IC) are present in most of the corneas long after infective virus has disappeared. These viral components are highly immunogenic and potentiate production of proinflammatory cytokines and chemokines via Toll-like receptors (TL...

journal_title：Seminars in ophthalmology

authors： Hayashi K,Hooper LC,Hooks JJ

更新日期：2008-07-01 00:00:00

abstract：:The management of a patient with a suspected posterior communicating artery aneurysm is discussed with emphasis on neuroimaging including magnetic resonance angiography (MRA), computed tomography angiography (CTA) and intra-arterial digital subtraction angiography (DSA). This paper underscores the advantages and disad...

journal_title：Seminars in ophthalmology

authors： Vaphiades MS,Cure J,Kline L

更新日期：2008-05-01 00:00:00

abstract：:A 50-year-old man presented with uncontrolled erythroclastic glaucoma and recurrent vitreous hemorrhage from a previously irradiated choroidal melanoma. Despite trabeculectomy, intraocular pressure became uncontrolled due to increasing bleeding from the melanoma. The vitreous hemorrhage became voluminous and could not...

journal_title：Seminars in ophthalmology

authors： Ferreyra HA,Goldbaum MH,Weinreb RN

更新日期：2008-03-01 00:00:00

abstract：:Leber congenital amaurosis (LCA) is a congenital retinal dystrophy that was first described almost 150 years ago. LCA still remains an important cause of blindness with about 20% of children in schools for the blind being affected by it. LCA has genetic heterogeneity and the study of this disease is elucidating the ge...

journal_title：Seminars in ophthalmology

authors： Ahmed E,Loewenstein J

更新日期：2008-01-01 00:00:00

abstract：:We report two cases of primary uveal melanoma with metastatic involvement of the contralateral eye. Two female patients presented with primary choroidal melanoma. In the first case, primary enucleation of the affected eye was performed. Two years later, systemic tumor spread with contralateral choroidal melanoma was d...

journal_title：Seminars in ophthalmology

authors： Bourla DH,Young TA

更新日期：2007-07-01 00:00:00

abstract：:The purpose of this article is to report a case in which a double hemispheric retinal vein occlusion (HSRVO) occurred in the same eye, involving firstly the superior half and later the inferior half of the retina. A 63-year-old woman with ill-controlled hypertension had been diagnosed with central retinal vein occlusi...

journal_title：Seminars in ophthalmology

authors： Battaglia Parodi M,Iacono P,Ravalico G

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:To describe a case of cotton wool spots associated with interferon beta-1a treatment. METHODS:Observational case report. RESULTS:A 40-year-old man with a history of multiple sclerosis was on interferon beta-1a. He presented with cotton wool spots on fundus exam, which resolved and then recurred all while on t...

journal_title：Seminars in ophthalmology

authors： Longmuir R,Lee AG,Rouleau J

更新日期：2007-01-01 00:00:00

abstract：:A 45-year-old male pedestrian was struck by a motor vehicle moving at high speed. Upon initial assessment, the patient scored a 3T on the Glasgow Coma Scale. The patient suffered multiple facial and sinus fractures, a right orbital wall fracture, and a depressed open frontal skull fracture with visible brain parenchym...

journal_title：Seminars in ophthalmology

authors： Marriott E,Jay WM

更新日期：2007-01-01 00:00:00

abstract：:Guillain-Barre syndrome (GBS) is characterized by an ascending muscle paralysis with progressive loss of muscle stretch reflexes. Annually, approximately 2.4 cases per 100,000 population of GBS are reported. Variant forms do exist. These include the Fisher syndrome, GBS with ophthalmoplegia, Bickerstaff's brainstem en...

journal_title：Seminars in ophthalmology

authors： Chaudhry F,Gee KE,Vaphiades MS,Biller J,Jay W

更新日期：2006-10-01 00:00:00

abstract：:Primary intraocular lymphoma (PIOL) is a type of primary central nervous system lymphoma (PCNSL). It is the most common neoplastic masquerade syndrome involving the eye. Its protean ocular manifestations, plus in many cases the initial positive response to corticosteroid therapy for presumed uveitis, delay accurate di...

journal_title：Seminars in ophthalmology

authors： Choi JY,Kafkala C,Foster CS

更新日期：2006-07-01 00:00:00

abstract：:It is now widely acknowledged that vasculogenesis and immunogenic inflammation are intricately related in many tissues. However, less understood is to what extent blood (heme) angiogenesis (HA) and lymphangiogenesis (LG) are differentially regulated, and in turn contribute potentially to different aspects of adaptive ...

journal_title：Seminars in ophthalmology

authors： Dana MR

更新日期：2006-01-01 00:00:00

abstract：:Syphilis is a sexually transmitted, chronic, systemic infection caused by the spirochete Treponema pallidum. If left untreated, the disease progresses through four stages, with the potential to cause significant morbidity to any major organ of the body. Frequent syphilitic ocular manifestations, which can occur at any...

journal_title：Seminars in ophthalmology

authors： Kiss S,Damico FM,Young LH

更新日期：2005-07-01 00:00:00

abstract：:Secondary causes of ocular surface disease are-to a large extent-due to disorders of the ocular adnexae. The main pathomechanisms involved include exposure, abrasion and malnutrition, resulting from a multitude of disorders such as ec- or entropion (e.g. in cicatrizing conjunctivitis), lid retraction and severe aqueou...

journal_title：Seminars in ophthalmology

authors： Geerling G,Borrelli M

更新日期：2005-04-01 00:00:00

abstract：:Many ocular diseases, such as retinitis pigmentosa and age-related macular degeneration, reflect damage to specific cells that are not normally repaired or replaced. Preliminary results of animal studies suggest that these degenerative diseases may be treatable by transplantation of healthy fetal cells. However, obtai...

journal_title：Seminars in ophthalmology

authors： Haruta M

更新日期：2005-01-01 00:00:00

abstract：:Congenital grouped albinotic retinal pigment epithelial spots (CGARPES) is a rare retinal pigment epithelium disease with multiple, white spots, generally involving the peripheral retina, with variable angiographic pattern. A 46-year-old male affected by CGARPES underwent fluorescein angiography and indocyanine green ...

journal_title：Seminars in ophthalmology

authors： Battaglia Parodi M,Iacono P

更新日期：2004-09-01 00:00:00

abstract：:A 61-year-old female presented with a moderate decrease in vision in the left eye. The patient denied any other ocular or systemic symptoms related to giant cell arteritis. Visual acuity was 20/50 in the left eye with a 2+ relative afferent pupillary defect and markedly abnormal color vision. Dilated fundus examinatio...

journal_title：Seminars in ophthalmology

authors： Galasso JM,Jay WM

更新日期：2004-09-01 00:00:00

abstract：PURPOSE:To evaluate the characteristics of macular edema (ME) before and after radial optic neurotomy (RON) detected by optical coherence tomography (OCT), in patients with central retinal vein occlusion (CRVO). DESIGN:Interventional case series. METHODS:Five eyes of 5 patients affected by CRVO underwent RON. Complet...

journal_title：Seminars in ophthalmology

authors： Patelli F,Radice P,Zumbo G,Fasolino G,Marchi S

更新日期：2004-03-01 00:00:00

abstract：:Optic disc drusen are congenital and developmental anomalies of the optic nerve head seen commonly in clinical practice, often as an incidental ophthalmologic finding during routine exams. Optic disc drusen are a form of calcific degeneration in some of the axons of the optic nerve. Visual acuity is often not affected...

journal_title：Seminars in ophthalmology

authors： Davis PL,Jay WM

更新日期：2003-12-01 00:00:00

abstract：:The current management of acute post-operative endophthalmitis relies on microbial confirmation, intravitreal antibiotics, and vitrectomy. The endophthalmitis vitrectomy study (EVS) demonstrated that systemic antibiotics are not necessary in post-cataract/secondary intraocular lens (IOL) acute bacterial endophthalmiti...

journal_title：Seminars in ophthalmology

authors： Das T,Sharma S,Hyderabad Endophthalmitis Research Group.

更新日期：2003-09-01 00:00:00

abstract：:The purpose was to investigate the effect of decentered ablation in myopic corneal refractive surgery by simulation. Wavefront aberrations in a small pupil area (radius: 2 mm) for photopic vision and in a large pupil area (radius: 3 mm) for mesopic vision with simulated refractive surgery were analyzed using Zernike p...

journal_title：Seminars in ophthalmology

authors： Mihashi T

更新日期：2003-03-01 00:00:00

abstract：:Macular hole formation is a rare complication of cataract extraction. Although the exact etiology is unclear, macular holes can be classified into pre-existing holes that may not have been visible prior to cataract surgery, early stage macular holes that progressed to a more advanced stage, symptomatic holes following...

journal_title：Seminars in ophthalmology

authors： Ameli N,Lashkari K

更新日期：2002-09-01 00:00:00

abstract：:The onset of post-operative corneal melting and necrotizing scleritis in patients with rheumatoid arthritis and collagen vascular disease who undergo cataract surgery can have devastating ocular and systemic consequences. Even though ocular surface factors such as sicca and surgical trauma are among the important vari...

journal_title：Seminars in ophthalmology

authors： Perez VL,Azar DT,Foster CS

更新日期：2002-09-01 00:00:00

abstract：:Management of angle closure glaucoma requires an understanding of the underlying pathophysiologic mechanisms. Treatment is aimed at eliminating pupillary block and other causes of angle closure, re-opening the angle, and preventing further damage to the optic nerve by lowering intraocular pressure. Medical therapy pla...

journal_title：Seminars in ophthalmology

authors： Hoh ST,Aung T,Chew PT

更新日期：2002-06-01 00:00:00

abstract：:A wide variety of infectious agents are known to cause optic neuropathy. This article will consider the bacteria, spirochetes, fungi, and viruses that most commonly affect the optic nerve. Clinical presentation is variable, but some pathogens often produce a characteristic funduscopic pattern. Diagnosis is usually mad...

journal_title：Seminars in ophthalmology

authors： Golnik KC

更新日期：2002-03-01 00:00:00